State of the Art Facility

Isolation Equipment

PAPPL uses Heinkel Centrifuges for isolation of the solids. The isolation is carried out in contained manner with no exposure to the operator. The high level of automation involved means there is very little manual intervention required after the process has been initiated. The process control system and closed circuit TV allows for continuous remote monitoring of the operation from the control room. To ensure the centrifuging operation is carried out safely, the centrifuge system is protected by a continuous nitrogen purge and almost 200 safety interlocks.




Drying of isolated product


The isolated products are dried in vacuum pan dryers that use heating and vacuum to remove the residual moisture and solvent content from the product. The products from the dryers are discharged in a totally contained manner into IBCs.




Milling and Finished Goods Packout


This is the final step of an API manufacturing where the materials are milled to the correct particle size distribution. The milled materials are packed into fibre drums. The packed drums are then transferred to the warehouse for storage before sending it out to the customers. The milling and finished goods packout operation takes place in a controlled clean room environment which is designed to class 100,000 specification.




Solvent Recovery Systems


PAPPL has designed a solvent recovery system that promotes resource conservation, waste minimization, cost effectiveness and environment protection in the product manufacturing processes. The solvent recovery distillation columns are 22 meters in height and 1 meter in diameter. These design dimensions provide an efficient and effective way of recovering solvent.




End Of Line (EOL) Device


To ensure that the plant is environmentally friendly, exceeds local statutes, and meets Pfizer corporate regulations, the plant is equipped with an EOL (End Of Line) device. This system routes gas emissions from the process in the production building, tank farm and solvent recovery area to a thermal oxidizer where the high oxidation temperature of over 900° ensures full destruction of any solvent-laden gases into carbon dioxide and water vapor, which are environmentally safe.




Designed for Increased Capacity


The plant is designed to allow for a doubling of the site capacity to meet increasing demands with minimum disruptions and faster market response. Utilities such as the steam boilers, air compressors, cooling towers, chillers etc have in built capacity and piping considerations that allow for additional units to be installed with minimum disruption. The wastewater treatment plant is designed for more loading than one plant will deliver. The engineering, laboratories and administration offices have all been built with future expansion in mind.




Flexibility


The equipment within the plant is modular in its design. Each unit stands alone and is connected to the other units using a series of piping manifolds located on each floor of the building. The installation is not product specific. It is a multi purpose facility capable of manufacturing a range of products that are anticipated to be manufactured.





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